Skip to content

Reducing the risk of cognitive decline

What the 2024 Lancet Commission and WHO say about the modifiable factors that can lower dementia risk across life - and practical actions.

We cannot control every cause of dementia, but a large body of research says that addressing certain factors across life could prevent or delay a meaningful share of cases. The 2024 Lancet Commission estimates that around 45% of dementia cases could in principle be prevented or delayed by tackling 14 modifiable risk factors [Livingston G 2024] .

This is about lowering risk, not a guarantee - and it is never too early or too late to act [Livingston G 2024] .

The 14 factors

The Commission lists: lower education, hearing loss, high blood pressure, smoking, obesity, depression, physical inactivity, diabetes, excessive alcohol, traumatic brain injury, air pollution, social isolation, and - newly added in 2024 - untreated vision loss and high LDL cholesterol [Livingston G 2024] .

Practical actions

You do not need to fix everything. Pick what is realistic:

  • Move regularly. Aim toward 150 minutes of moderate activity a week if you can [World Health Organization 2019] .
  • Protect your hearing and vision - get tested, use hearing aids and glasses if needed.
  • Look after your heart numbers - blood pressure, cholesterol, blood sugar.
  • Stay socially connected and treat low mood; isolation and depression both matter.
  • Don’t smoke; keep alcohol low.
  • Keep learning and stay mentally active.

Focus on what you can change

Not everything is in our control, but several habits meaningfully shift the odds:

  • Stay physically active most days.
  • Keep blood pressure, cholesterol, and blood sugar in check.
  • Don’t smoke, and keep alcohol within limits.
  • Address hearing loss and stay socially connected.

Feed the brain

  • Favour a vegetable-rich, whole-food eating pattern.
  • Include beans, nuts, fish, and healthy fats.
  • Limit ultra-processed foods and added sugar.

Keep the mind and body engaged

  • Keep learning new things.
  • Stay in regular contact with others.
  • Protect your sleep.
  • Manage stress with calming routines.

Start small

You don’t need to change everything at once. Choose one habit from each area and build gradually - consistency matters more than intensity.

A balanced note

WHO rates the strength of evidence as varying by factor - strongest for physical activity and managing cardiovascular risk, with others more uncertain [World Health Organization 2019] . The encouraging message is that healthy habits help your whole body and brain, with little downside.

Turn this into action with Practice.

References

  1. 1. Livingston G, Huntley J, Liu KY, et al. (2024). Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. The Lancet. doi:10.1016/S0140-6736(24)01296-0
  2. 2. World Health Organization (2019). Risk reduction of cognitive decline and dementia: WHO guidelines. World Health Organization, Geneva. Link